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Fair Value Measurements Inter Transfers Between Levels Transfers between Level 1, Level 2 and Level 3 Accrued Expenses and Other Current Liabilities Schedule of Accrued Liabilities [Table Text Block] Amount of increase (decrease) in the operating lease right-of-use asset. 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Share Based Compensation Arrangement By Share Based Payment Award Options Aggregate Intrinsic Value [Abstract] Aggregate Intrinsic Value Net unrealized gains (loss) on marketable securities OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax Share-Based Payment Arrangement [Abstract] Accounts Payable, Current Accounts payable Accounts Payable, Current, Total Debt Instrument [Axis] Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Unvested ending balance Weighted Average Grant Date Fair Value, Unvested beginning balance Costs and Expenses Total operating expenses Debt Securities, Available-for-Sale, Noncurrent Long-term marketable securities Entity Small Business Entity Small Business Entity Shell Company Entity Shell Company Title of Individual [Axis] Title of Individual Investment Type [Axis] Investment Type Restricted Stock, Shares Issued Net of Shares for Tax Withholdings Vesting of restricted stock units, net of withholding, Shares Number of shares range percentage Share Based Compensation Arrangement By Share Based Payment Award Percentage Of Target Shares Earned Maximum Limit The maximum percentage of target performance shares that are eligible to be earned based on achievement of a total shareholder return target. Earnings Per Share [Text Block] Net Loss Per Share Commercial Paper [Member] Commercial Paper [Member] Entity Address, Address Line One Entity Address, Address Line One Cash and Cash Equivalents, Fair Value Disclosure Cash equivalents Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items] Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items] Scott T. Rottinghaus Scott T Rottinghaus [Member] Scott T Rottinghaus Subsequent Event Type [Domain] Income Statement Location [Axis] Income Statement Location Restricted Stock, Value, Shares Issued Net of Tax Withholdings Vesting of restricted stock units, net of withholding Long-Term Debt, Type [Axis] Net loss Net Income (Loss), Including Portion Attributable to Noncontrolling Interest Net Income (Loss), Including Portion Attributable to Noncontrolling Interest, Total Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] Fair Value, Liabilities Measured on Recurring Basis, Unobservable Input Reconciliation [Line Items] 2028 Lessee, Operating Lease, Liability, to be Paid, Year Five Fair Value, Inputs, Level 2 [Member] Level 2 [Member] Collaborative Arrangement and Arrangement Other than Collaborative [Table] Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table] Product and Service [Axis] Title of 12(b) Security Title of 12(b) Security Payments on royalty sale liability, net of imputed interest. Payments on Royalty Sale Liability, Net Of Imputed Interest Payments on royalty sale liability, net of imputed interest Investments [Domain] Investments Net Cash Provided by (Used in) Investing Activities [Abstract] Cash flows from investing activities State and Local Jurisdiction [Member] State Tax Reserve [Member] Nonmonetary Transactions [Abstract] Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term Options exercisable as of end of period Common Stock, Shares, Outstanding Common stock, shares outstanding Common Stock, Shares, Outstanding, Beginning Balance Common Stock, Shares, Outstanding, Ending Balance Share-Based Payment Arrangement [Text Block] Stock-Based Awards Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value Weighted Average Grant Date Fair Value, Cancelled Liability related to the sale of future royalties Accrued Royalties, Current Summary of the Liability Related to the Sale of Future Royalties Schedule of Changes in the Liability Related to the Sale of Future Royalties [Table Text Block] Tabular disclosure of the changes in the liability related to the sale of future royalties. Income Statement Location [Domain] Income Statement Location Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price Granted Document Type Document Type Net cash provided by investing activities Net Cash Provided by (Used in) Investing Activities Document Quarterly Report Document Quarterly Report Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period Cancelled Net cash used in financing activities Net Cash Provided by (Used in) Financing Activities Liability Related to the Sale of Future Royalties Liability Related to the Sale of Future Royalties [Text Block] The entire disclosure for liability related to the sale of future royalties. Entity Filer Category Entity Filer Category Increase (Decrease) in Other Noncurrent Assets Other long-term assets Increase (Decrease) in Accrued Liabilities Accrued expenses Increase (Decrease) in Accrued Liabilities, Total Accrued Liabilities, Current [Abstract] Accrued expenses: Payments to Acquire Marketable Securities Purchase of marketable securities Payments to Acquire Marketable Securities, Total Total other income, net Nonoperating Income (Expense) Capital Expenditures Incurred but Not yet Paid Purchases of fixed assets included in accounts payable and accrued expenses Liabilities Total liabilities Equity, Attributable to Parent Ending Balance Beginning Balance Total stockholders' equity Net loss Net loss Net loss Other income (expense): Nonoperating Income (Expense) [Abstract] Interest expense, net of capitalized interest Interest expense Interest Expense Interest Expense, Total Business Description and Basis of Presentation [Text Block] Nature of the Business and Basis of Presentation Corporate Debt Securities [Member] Corporate Bonds [Member] Statement of Financial Position [Abstract] Weighted Average Number of Shares Outstanding, Diluted Diluted Weighted average common shares outstanding —diluted Amortized Cost Debt Securities, Available-for-Sale, Amortized Cost Amortized Cost Use of Estimates, Policy [Policy Text Block] Use of Estimates Income Tax Disclosure [Text Block] Income Taxes Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price Outstanding Outstanding Schedule of Earnings Per Share, Basic and Diluted [Table Text Block] Basic and Diluted Net Loss Per Share Attributable to Common Stockholders Income Tax Authority [Axis] Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items] Fair Value Disclosures [Abstract] Fair Value Hierarchy and NAV [Axis] Level 2 [Member] Preferred stock that may not be exchanged into common shares or other types of securities at the owner's option. Series One Non Convertible Preferred Stock [Member] Series 1 Nonconvertible Preferred Stock [Member] Measurement Frequency [Domain] Payments to Acquire Property, Plant, and Equipment Purchase of property and equipment Payments to Acquire Property, Plant, and Equipment, Total Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period Vested Employee-related Liabilities, Current Accrued payroll and related expenses Employee-related Liabilities, Current, Total Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at beginning of period Cash, cash equivalents and restricted cash at end of period Income Tax Disclosure [Abstract] Marketable Securities [Table Text Block] Fair Value of Available-for-Sale Marketable Securities by Type of Security Royalty purchase agreement interest rate Royalty purchase agreement annual imputed interest rate Royalty Purchase Agreement Interest Rate Royalty purchase agreement interest rate.